Companies / Amerigo Scientific / Recombinant Human EIF2AK3 (N-GST tag)
Amerigo Scientific

Recombinant Human EIF2AK3 (N-GST tag) | Amerigo Scientific

EIF2AK3 phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2) leading to its inactivation and a rapid reduction of translational initiation and repression of global protein synthesis. EIF2AK3 is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. EIF2AK3 plays a major role in the ability of cells to adapt to ER stress and is also involved in an integrated adaptive response to hypoxic stress in HeLa cells. EIF2AK3 functions in iron homeostasis and may play a role in hemolytic and inflammatory anemia.

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ABOUT THE COMPANY

Amerigo Scientific is a distribution company focused on providing critical products and services to the biomedical and life science research communities. Although a new company, Amerigo Scientific's founder has had more than 20 years of rich experience in the biomedical and biochemical fields, and has established close contacts with key personnel in...
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