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Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
Creative Biolabs
Recombinant Human Anti-CD33 x Human Anti-CD64 Bispecific Antibody (scFv4-Ig) | Creative Biolabs
Recombinant Anti-CD33 x Anti-CD64 Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-CD33 scFv is fused to the CH1 domain of a heavy chain and another anti-CD64 scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can retarget neutrophils cells to tumor cells. It is designed for the research of Acute myeloid leukemia (AML); Ulcerative Colitis (UC); Myelodysplastic syndromes (MDS); Gastric cancer therapy.
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