Name: Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Fv-IgG)
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Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Fv-IgG) | Creative Biolabs

Recombinant Anti-HER1 x Anti-HER3 Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-HER1 IgG with similar domains from an anti-HER3 antibody via short peptide linkers, or vice versa. This BsAb can bind and inactivate two receptors simultaneously. It is designed for the research of Head and neck cancer; Colorectal cancer therapy.