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Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
Creative Biolabs
Recombinant Anti-Ang2 x Anti-VEGFA Bispecific Antibody (Fv-IgG) | Creative Biolabs
Recombinant Anti-Ang2 x Anti-VEGFA Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-Ang2 IgG with similar domains from an anti-VEGFA antibody via short peptide linkers, or vice versa. This BsAb is capable of inhibiting two proangiogenics fators and a combined blockade of them has a greater inhibitory efficacy compared with inhibition of either factor alone. It is designed for the research of Colorectal cancer (CRC); Solid tumors; Wet AMD (Age-related macular degeneration); Diabetic macular edema therapy.
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