Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
Recombinant Anti-DNMT1 x Anti-SHH Bispecific Antibody (Diabody) is designed to be expressed as two polypeptide chains respectively. The two chains are cross-over pairing to form a dimer. It contains a His-tag for affinity purification. This BsAb can bind two factors simultaneously, block Hedgehog binding to PTCH, downregulate of DNMT1 and block DNA methylation. It is designed for the research of Hormone refractory breast cancer (HRBC) therapy.
Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.