Amerigo Scientific

T-VDA epi | Amerigo Scientific

Covalent modifications of DNA (e.g. cytosine methylation) or of histone proteins (e.g. lysine acetylation, lysine and arginine methylation, serine and threonine phosphorylation, and lysine ubiquitination and sumoylation) play central roles in many types of epigenetic regulation. Epigenetic factors that produce these modifications can be affected by development (in utero, childhood), environmental chemicals, drug/pharmaceuticals, ageing and diet which in turn can lead to cancer, autoimmune diseases, neurodegenerative disorders and diabetes. Given the large number of epigenetic factors, identifying small molecules and biologics with satisfactory selectivity profiles presents a huge challenge for epigenetic target drug discovery./

• Venoms are supplied lyophilised in Echo qualified acoustic source plates (Labcyte Inc) and are useable on any SBS footprint liquid handling device or by hand.

• 384-well format has 200ng venom fraction per well, suggested dilution 20µl as hit fractions are typically active at 5µg/ml and below.

• 1536-well format also available.

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ABOUT THE COMPANY

Amerigo Scientific is a distribution company focused on providing critical products and services to the biomedical and life science research communities. Although a new company, Amerigo Scientific's founder has had more than 20 years of rich experience in the biomedical and biochemical fields, and has established close contacts with key personnel in...
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