Companies / Amerigo Scientific / Recombinant Human GLK (N-GST tag)
Amerigo Scientific

Recombinant Human GLK (N-GST tag) | Amerigo Scientific

GLK is a member of the STE20 family of serine/threonine protein kinases and contains N-terminal catalytic domain and C-terminal regulatory domain. GLK is upstream of the MEKK1 target and is stimulated by UV radiation and TNF-? and can lead to the activation of the JNK signaling pathway. GLK can directly activate PKC-? during TCR signaling and people with systemic lupus erythematosus show considerable enhanced GLK expression and activation of PKC-? and the kinase IKK in T cells. GLK can act as a pro-apoptotic kinase which orchestrates activation of BAX via the concerted posttranscriptional modulation of PUMA, BAD, and BIM.

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ABOUT THE COMPANY

Amerigo Scientific is a distribution company focused on providing critical products and services to the biomedical and life science research communities. Although a new company, Amerigo Scientific's founder has had more than 20 years of rich experience in the biomedical and biochemical fields, and has established close contacts with key personnel in...
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