Companies / Amerigo Scientific / Recombinant Human FGFR4 (N-GST tag)
Amerigo Scientific

Recombinant Human FGFR4 (N-GST tag) | Amerigo Scientific

FGFR4 is a member of the fibroblast growth factor receptor family which play a role in mitogenesis and differentiation. FGFR4 preferentially binds acidic fibroblast growth factor and is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. FGFR4 gene expression is up-regulated in doxorubicin-treated, apoptosis-resistant cancer cell clones. Ectopic expression of FGFR4 in cancer cells leads to reduced apoptosis sensitivity on treatment with doxorubicin or cyclophosphamide, whereas knockdown of endogenous FGFR4 expression in breast cancer cell lines has the opposite effect.

Reviews


No reviews yet

ABOUT THE COMPANY

Amerigo Scientific is a distribution company focused on providing critical products and services to the biomedical and life science research communities. Although a new company, Amerigo Scientific's founder has had more than 20 years of rich experience in the biomedical and biochemical fields, and has established close contacts with key personnel in...
READ MORE