This compilation of webinars touch on the various human diseases are most commonly attributed to the subject matter of microbiology, as well as the many microbes that are also responsible for numerous beneficial processes.
For the past years, my laboratory has been working on microfluidic devices to enable the analysis of single cells. Our technology of choice has been droplet microfluidics that encapsulates s...
Emerging viruses like SARS, SARS-CoV-2, MERS-CoV, Hendra, Nipah, West Nile, sin nombre, LuJo, MERS, Powassan, dengue, chikungunya, zika, Ebola, and Marburg pose a growing threat to public he...
Droplet generators are at the heart of many microfluidic devices developed for life science applications but are difficult to tailor to each specific application. The high fabrication costs,...
In recognition of Pancreatic Cancer Awareness Month, join us to explore how cutting-edge technologies are transforming our understanding of pancreatic ductal adenocarcinoma (PDAC), one of th...
Self-amplifying RNA replicons are promising candidates for next generation vaccines against human coronaviruses with pandemic potential. Self-amplification of RNAs in host cells generates mo...
The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
Spatial proteomics represents a revolutionary frontier in molecular biology, enabling researchers to explore protein expression while preserving the critical spatial context of tissue archit...
Microfluidic technologies have opened up new possibilities for ultra-low volume, and ultrafast assays, compared to bulk-scale counterparts. We have been focused on developing new tools for d...
The global demand for point-of-care testing (POCT) for diagnosing infectious diseases is growing. Bringing the test directly to the person needing the result greatly reduces the turn-around-...
Ebola virus executes its replication cycle through a tightly orchestrated sequence of events, but the host factors that govern the timing of these steps have remained poorly defined. In this...
Intestinal epithelial cells lining the surface of our gastro-intestinal tract form a tight monolayer which serves as the primary barrier separating us from the luminal content of the gut. Th...
Macrophages have been implicated in both the resolution and progression of influenza, but the drivers of these outcomes are poorly understood. We probed mouse lung transcriptomic datasets us...
We live in a revolutionary era during which technology is leading to amazing advances in medicine. Parallel and aided by the development of artificial intelligence (AI) are the emergence of...
Infectious diseases have been a major threat to human health throughout history, causing significant economic damage worldwide. In modern medicine, quickly and accurately identifying the ger...
For centuries, humans have become infected with endemic circulating Coronaviruses (hCoV), typically repeatedly throughout life. To understand how these respiratory infections establish CD4 T...
The vaginal microbiome is a critical component of female health. More than 30% of people with vaginas suffer from imbalances in the microbiome (e.g. bacterial vaginosis, yeast infections, an...
The gut microbiota has been proposed to affect the risk and prognosis of various health outcomes. Related to pregnancy, existing studies suggest that pregnant women have a distinct microbiot...
bacteriovorus is a predatory bacterium that preys on Gram-negative bacteria. B. bacteriovorus invades the prey-cell periplasm – the space between the inner and outer membrane – l...
Analysis of community wastewater has been shown to be an effective method for tracking the prevalence of SARS-COV-2. Our group has developed techniques for sequencing a portion of the SARS-C...
Traditional hybridoma and phage display methods have failed to yield therapeutic antibodies against difficult targets like most GPCRs and ion channels. This presentation will introduce Berke...
The tumor-associated microbiota is an inherent component of the tumor microenvironment across various human cancer types1. Although members of tumor-associated microbiomes can be identified t...
The regions of our genome responsible for encoding the genes that regulate our immune response are some of the most complex and polymorphic known. This complexity encompasses multiple types...
In the rapidly expanding landscape of molecular diagnostics, the focus is shifting from top to bottom, with a redirection from post-pandemic respiratory testing to developments in gastrointe...
RNA viruses use a variety of interactions with host proteins to gain entry, to evade immune responses, to promote viral replication, and to promote viral egress and spread. These interaction...
Prompt and early diagnosis of sexually transmitted infections (STIs) is important to enable appropriate treatment and help prevent further transmission....
Health economists are great at calculating a value-based price for diagnostic tests. Given the unexpected supply and demand for SARS-CoV-2 tests during the pandemic, efficient allocation of...
Over 80% of opportunistic infections in humans are caused by microbial biofilms. Traditional methods of study for these infections have focused on single species yet there is a wealth of evi...
For the past years, my laboratory has been working on microfluidic devices to enable the analysis of single cells. Our technology of choice has been droplet microfluidics that encapsulates s...
