Name: "Anti-GM2 (X9X153) h(CD28-41BB-CD3_) CAR, pCDCAR1"
Availability: InStock

"Anti-GM2 (X9X153) h(CD28-41BB-CD3_) CAR, pCDCAR1" | Creative Biolabs

Creative biolabs has developed Lentiviral CAR vector pCDCAR1 GM2 (X9X153) h(28BB_), which is constructed for the engineering of T cells to target human GM2. The T cells are genetically modified through transduction with a Lentiviral vector expressing scFv of anti-GM2 antibody linked to a CD28 transmembrane domain/ endodomain and CD137 (4-1BB), CD3-zeta signaling domains. And the vector product was designed for the treatment of Lung Cancer, Neuroblastoma, Glioma, Melanoma, Malignant Mesothelioma.