Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
Recombinant Anti-CD3 x Anti-PD1 Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-CD3 antibody are fused to the C terminus of an anti-PD1 IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can retarget T cells to tumor cells. It is designed for the research of Esophageal cancer; Hodgkin lymphoma; Renal cell cancer (RCC); Mesothelioma; Head and neck squamous cell cancer (HNSCC); Anal cancer; Gastric cancer; Hepatocellular cancer; Nasopharyngeal cancer; Non-small cell lung cancer (NSCLC); Solid tumors therapy.
Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.