Companies / Creative Biolabs / "Anti-TEM8_ERBB2 (SB5_FRP5) h(CD28-CD3_) TanCAR, pCDCAR1"
Creative Biolabs

"Anti-TEM8_ERBB2 (SB5_FRP5) h(CD28-CD3_) TanCAR, pCDCAR1" | Creative Biolabs

The vector of anti-TEM8_ERBB2 tandem chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human TEM8 and ERBB2. The T cells are genetically modified through transduction with a lentiviral vector expressing bivalent scFv of anti-TEM8_ERBB2 antibody and linked to CD28 and CD3_ signaling domains. And the vector product was designed for the treatment of TEM8+/ERBB2+ cancer.

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ABOUT THE COMPANY

Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.