Name: "Anti-PMEL (15F2) h(CD28-CD3_) CAR, pSBCAR1"
Availability: InStock

"Anti-PMEL (15F2) h(CD28-CD3_) CAR, pSBCAR1" | Creative Biolabs

Sleeping Beauty (SB) transposon, a type of nonviral integrative vectors, provides an alternative to modify primary T cells. Creative biolabs has developed SB transposon CAR vector pSBCAR1 PMEL (15F2) h(28_), which is constructed for the engineering of T cells to target human PMEL. The T cells are genetically modified through transduction with a nonviral vector expressing scFv of anti-PMEL antibody linked to CD28 and CD3_ signaling domains. And the vector product was designed for the treatment of Melanoma.