Companies / Creative Biolabs / "Anti-CD44 v6/v7 (1.1ASML) h(CD28-CD3_) CAR, pMMLV"
Creative Biolabs

"Anti-CD44 v6/v7 (1.1ASML) h(CD28-CD3_) CAR, pMMLV" | Creative Biolabs

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Recombinant Moloney murine leukemia virus (MMLV) retroviral vectors serve as efficient viral vector tools for introducing genes permanently into a wide variety of dividing cells, and provide an alternative to modify primary T cells. Creative biolabs has developed retroviral CAR vector pMMLV CD44 v6/v7 (1.1ASML) h(28_), which is constructed for the engineering of T cells to target human CD44 v6/v7. The T cells are genetically modified through transduction with a retroviral vector expressing scFv of anti-CD44 v6/v7 antibody linked to a CD28 transmembrane domain and CD3-zeta signaling domains. And the vector product was designed for the treatment of (Metastasized) colon cancer, soft tissue sarcoma (STS).

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Creative Biolabs

Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields. 

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