Companies / Creative Biolabs / "Anti-CD16 (B73.1) h(CD28-CD3_) ATCR, pCDATCR1"
Creative Biolabs

"Anti-CD16 (B73.1) h(CD28-CD3_) ATCR, pCDATCR1" | Creative Biolabs

The vector of anti-CD16 Antibody-Coupled T cell Receptor (ACTR) is constructed for the engineering of T cells to target Fc fragment of a therapeutic antibody. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD16 antibody linked to co-stimulation (CD28 or 4-1BB) and CD3_ signaling domains. The universal - ACTR T cell can attack many different cancers.

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ABOUT THE COMPANY

Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.