Companies / Creative Biolabs / "Anti-U1-RNP h(CD28-CD3_) CAART, pCDCAAR1"
Creative Biolabs

"Anti-U1-RNP h(CD28-CD3_) CAART, pCDCAAR1" | Creative Biolabs

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CAAR-Ts represent a targeted approach to therapy of antibody-mediated autoimmune diseases, with the potential for generation of long-term memory CAAR-Ts that can potentially cure disease. Autoantigen-based chimeric immunoreceptors (CAAR) can direct T cells to kill autoreactive B lymphocytes through the specificity of the B cell receptor (BCR). The vector of anti-U1-RNP chimeric autoantigen receptor (CAAR) is constructed for the engineering of T cells to target Human U1-RNP. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-U1-RNP antibody linked to Mixed connective tissue
disease.

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ABOUT THE COMPANY

Creative Biolabs

Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields. 

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