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Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
Creative Biolabs
Recombinant Anti-Ad Fiber Knob x Anti-CEA Bispecific Antibody (Tandem scFv) | Creative Biolabs
Recombinant Anti-Ad fiber knob x Anti-CEA Bispecific Antibody (Tandem scFv) is designed to be expressed as a scFv fromti-Ad fiber knob antibody variable domains fused with a scFv from an anti-CEA antibody variable domains. It contains a His-tag at the C/N terminus for affinity purification. The BsAb exits as monomer in reducing and non-reducing conditions. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing.
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