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BOC Sciences specializes in small molecule synthesis, biosynthesis, purification, and characterization. It provides a wide range of research chemicals and biochemicals, including inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities and metabolites, APIs, natural compounds, ADCs, stem cell molecules and chiral compounds.
BOC Sciences
Gemtuzumab | BOC Sciences
Gemtuzumab (brand name Mylotarg) is a monoclonal antibody used in the treatment of acute myeloid leukemia (AML). Gemtuzumab targets CD33, a protein found on the surface of myeloid cells, including leukemic cells in AML. By binding to CD33, gemtuzumab may induce antibody-dependent cellular cytotoxicity (ADCC), leading to destruction of CD33-positive leukemia cells. Gemtuzumab is indicated for the treatment of newly diagnosed CD33-positive AML in adults, as well as for relapsed or refractory CD33-positive AML in both adults and pediatric patients.
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