Reviews
BOC Sciences specializes in small molecule synthesis, biosynthesis, purification, and characterization. It provides a wide range of research chemicals and biochemicals, including inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities and metabolites, APIs, natural compounds, ADCs, stem cell molecules and chiral compounds.
BOC Sciences
Natalizumab | BOC Sciences
Natalizumab, a recombinant and humanized IgG4 monoclonal antibody, binds to _4_1-integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1). It is used to treat relapsing remitting multiple sclerosis and Crohn's disease. It is also the first targeted therapy to block an important mechanism for lymphocyte entry to the CNS and thus prevent acute demyelinating relapses.
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