Tildrakizumab is a monoclonal antibody used in the treatment of moderate to severe plaque psoriasis, a chronic autoimmune skin condition characterized by red, itchy, and scaly patches on the skin. Tildrakizumab targets and blocks interleukin-23 (IL-23), a cytokine involved in the inflammatory pathway that drives psoriasis. By inhibiting IL-23, tildrakizumab helps to reduce the inflammation and abnormal skin cell growth associated with psoriasis. It is indicated for the treatment of adults with moderate to severe plaque psoriasis who are candidates for systemic therapy or phototherapy. Tildrakizumab is typically used in patients who have not responded adequately to other treatments or have experienced intolerable side effects.